Brain’s immune system may remove plaques

Culminating years of investigation, a team at the University of Rochester recently reported in the Journal of Neuroinflammation their findings that microglia, “tricked” into action, reduced more than 60 percent of amyloid beta in the brains of mouse models. Microglia cells are part of the brain’s immune system that defend against inflammation caused by injury and infection.  Absent brain inflammation, researchers used cytokine to activate the microglia. Lead investigator Dr. Kerry O’Banion said, “. . .the immune system can be manipulated. . .potentially pointing to a new therapeutic approach to Alzheimer’s disease. . . .it is clear that microglia play an important role in the removal of amyloid beta from the brain and may represent a novel approach to treating this disease.”