Alzheimer’s Disease Begins Many Years before Symptoms Appear

A newly published research paper in the journal Alzheimer’s and Dementia (July 2015) has confirmed the information I stated in my book Not Going Gently. In fact, the data show that changes in biomarkers may begin between the ages of 20 and 30, much earlier than the two to three decades I had stated. The researchers, Shannon L. Risacher, PhD, assistant professor of radiology and imaging science  and Andrew J. Saykin, PsyD, director of the Indiana Alzheimer’s Disease Center and the Indiana University Center on Neuroimaging Initiative, “provide evidence for focusing research, and eventually treatment, on people at risk of Alzheimer’s long before the disease is diagnosed.” They add that effective interventions  need to be applied many years before symptoms appear. These interventions (such as those I described for prevention) include exercise, diet modification, cognitive stimulation, sleep, and other lifestyle factors.